Production AI and genomics for life sciences.

I help healthcare and life-sciences teams take AI and genomic modeling from research to reliable, deployed systems — with an emphasis on correctness, auditability, and deployment in regulated environments.

Agentic AI Genomics & sequence modeling ML infrastructure PhD-led, end to end

A decade-plus of hands-on engagements across the industry — delivered as one senior consultant, from research through production.

Top-20 pharmaceutical National health insurer Venture-backed biotech Academic medical centers Funded research programs
What I do

Depth where it's hard to find.

A single expert across the full arc of a project — from modeling strategy to systems that run in production.

Agentic AI for high-stakes work

Auditable, human-in-the-loop AI systems that pair deterministic computation with LLM judgment — and deploy on-prem or fully offline in regulated clinical and enterprise settings.

Genomics & sequence modeling

Genomic and variant interpretation, genotype-to-phenotype and drug-resistance prediction, and protein language models for sequence-based property and specificity prediction.

ML under real-world constraints

Rigorous modeling with the small, imbalanced, and expensive-to-label data that real biomedical work produces — and honest assessment of what the data can and can't support.

Data & AI infrastructure

Production software and data engineering, cloud platforms, APIs, and agent orchestration — the pipelines and plumbing that make AI and data systems dependable enough to ship.

How I work

Built to be trusted in production.

A few principles that hold across every engagement, especially the high-stakes ones.

01 Deterministic where it counts

The arithmetic and rules are computed, not guessed. AI is reserved for judgment, so results stay correct and reproducible.

02 Auditable by default

Every recommendation traces back to its evidence. The reasoning path is the explanation — no black boxes in high-stakes decisions.

03 Deployable in the real world

Systems designed to run on-prem or fully offline, inside the security and compliance constraints of regulated environments.

04 One expert, end to end

A single PhD-led point of contact who takes the work from research through a live, tested, deployed system.

Engagements

Ways to work together.

Technical assessment

A focused engagement to scope data readiness, model feasibility, and the right architecture before committing to a build.

Prototype to production

End-to-end design and delivery of ML systems, data pipelines, and cloud infrastructure — from proof of concept to deployment.

Advisory, review & grant support

Ongoing technical guidance on ML strategy and system design, plus scientific and grant writing behind funded research.

About

Ted Mellors, PhD

TRM Systems is a technical consulting practice built around a decade and a half of work moving complex machine-learning and data systems from research into production across academia, biotech, and pharma.

That work centers on building AI and genomic-modeling systems that are correct, maintainable, and trustworthy enough to deploy in regulated environments.

Recent work spans auditable agentic AI for clinical decision support, genotype-to-phenotype and drug-resistance modeling, protein language models, production data engineering for large healthcare organizations, and the scientific and grant writing behind funded research.

Domains served

  • Agentic clinical decision support
  • Infectious disease & genomic epidemiology
  • Biologics & drug discovery
  • Clinical & pharmacy ML
  • Genomics & sequence modeling

Have a hard problem in AI or genomics?

Tell me what you're working on. I'll tell you honestly whether and how I can help.

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